We are aware that tons of people are scared of taking injections. Most of us would think children come into this category. But, adults are no exception in this case. As a result, there is decreased medication adherence. In case of injections, greater care is required compared to other dosage forms of drugs. Qualified personnel is necessary to inject drugs. In patient’s perspective, it is painful and inconvenient. To address certain problems associated with injections, researchers since years are trying to find an alternative to administer injectable drugs.

As a result of years of hard work, A Silicon valley based R&D center – Rani Therapeutics have developed a new drug delivery system that could replace injectable medications in near future. It is called the “RaniPill”. According to Mir Imran Chairman and CEO of Rani Therapeutics “RaniPill is a mini swallowable auto injector” RaniPill would be a convenient option of treatment in patients suffering from chronic conditions like Rheumatoid arthritis, osteoporosis, diabetes, hemophilia and multiple sclerosis as it replaces the regular need for injections.

Drugs which are broken down in the stomach are given through injections to help it reach the site of action. In case of RaniPill the injectable drug is packed in a capsule that has a special pH sensitive coating to enable its passage through the stomach without the process of dissolving. It reaches small intestine and dissolves. The less acidic environment of small intestine compared to stomach justifies this action. Fluid enters the capsule on dissolving, this triggers a tiny, hot-dog shaped plastic bag which is self-inflatable. As the plastic bag expands, the plastic balloon aligns itself perpendicular to the intestinal wall and pushes in a short, drug-filled needle, delivering the injection. The needle is made of sugar thus, it dissolves and the plastic is excreted. The company expects RaniPill to get approval in next three years and we can expect it to arrive into market within 10 years.

source: https://www.ranitherapeutics.com