Pharmachronicles

Top Menu

  • Home
  • Our Blog
  • Contact Us

Main Menu

  • Home Page
  • STUDENTS ZONE
  • Syllabus
  • Seminars & conferences
  • Online classes
    • Register
Sign in / Join

Login

Welcome! Login in to your account
Lost your password?

Lost Password

Back to login
  • Home
  • Our Blog
  • Contact Us

logo

  • Home Page
  • STUDENTS ZONE
  • Syllabus
  • Seminars & conferences
  • Online classes
    • Register
  • Resurgence of COVID-19 in Hong Kong and Singapore: A New Wave Driven by Waning Immunity and Emerging Variants

  • How Pharmacists Support Chronic Disease Management in the Community

  • OTC Medications: Safe Use, Common Mistakes, and Pharmacist Guidance

  • Pharmacovigilance Explained: Why Reporting Adverse Drug Reactions Saves Lives

  • Indian CDMOs Gain Global Momentum Amid Pharma’s Shift from China

BLOGS
Home›BLOGS›Can biotin manipulate lab test

Can biotin manipulate lab test

By admin
August 28, 2018
1665
0
Share:

 

The FDA  warns that high doses of vitamin B7, or biotin, in dietary supplements can interfere with hundreds of common lab tests — including some that emergency room doctors rely on to diagnose a heart attack. The problem has led to at least one death.Biotin is in many multivitamins. It’s also sold in formulas that are marketed to improve hair and nail growth. A 5- to 10-milligram dose — an amount that’s commonly added to supplements — is 166 times to 333 times more than the 30 micrograms most people need in their diets every day.Doctors sometimes prescribe high doses of biotin to treat nerve pain called neuropathy. It is also being studied as a treatment for multiple sclerosis.In some cases, extra biotin causes falsely high results on tests. In others, it causes the results to read as falsely low.That’s true with some ways to detect a protein called troponin, which rises after heart muscle has been damaged. Doctors use the troponin test in the emergency room to find out whether a patient’s chest pain is from heartburn or a heart attack.The FDA says a patient who was taking high levels of biotin died when a troponin test failed to show he was having a heart attack.Too much biotin in lab tests for thyroid hormones has led doctors to diagnose Graves’ disease in children and adults. Graves’ is an autoimmune disease that causes too much thyroid hormone in children and adults. Biotin in supplements can also affect tests for heart failure, pregnancy, cancer, and iron-deficiency anemia.Experts say the problem is not new.“In the lab community, people have known about this for a long time,” said Danni Li, PhD, director of clinical chemistry at the University of Minnesota Medical Center.

Li and her colleagues demonstrated this problem with an experiment. They asked six healthy adults to take 10 milligrams of biotin as a dietary supplement for a week. They tested their blood before and after they took the supplements for nine different hormones, a cancer marker, and iron. About 40% of the tests were thrown off by the supplements. Their study was published in September.

“For the last couple of years, I have been trying to raise the profile of this issue and get it to the attention of people who might be able to fix it. I’m glad to see this [FDA warning]” says Earle Holmes, PhD, a professor of molecular pharmacology and therapeutics at Loyola University School of Medicine in Maywood, IL.

Holmes and his team reviewed 374 tests that run on some of the most popular lab testing machines in the U.S. He found that 221 of them use biotin in their test. About 80 of these tests came with instructions that indicated they could be skewed by extra biotin in a patient’s blood.

The FDA says it is “working with stakeholders to better understand biotin interference with laboratory tests, and to develop additional future recommendations for safe testing in patients who have taken high levels of biotin when using laboratory tests that use biotin technology.”

To stay safe, Li says patients should check their vitamin bottles for biotin. Learn how much you’re taking, and tell your doctor you’re taking it at your next visit. She says lab directors can sometimes change tests if they think biotin might be a problem.

“This is a message that needs to get out,” says Lynn Burmeister, MD, an endocrinologist and associate professor of medicine at the University of Minnesota.

Biotin In Your Diet

Biotin is found in liver, eggs, fish, meat, nuts, seeds and some vegetables.

 For patients that have lab tests planned, she tells them to stop taking their supplements.

“If I can control what my patients are doing, I tell them to stop biotin for 1 week,” Burmeister says.

Other doctors say it’s probably also wise to consider whether you need to be taking biotin at all. Foods containing the vitamin include liver, egg yolks, fish, meat, seeds, nuts, and some vegetables, such as sweet potatoes.

“Biotin is in many supplements sold to improve skin and hair; however, the science supporting biotin for these indications is quite weak, so I don’t recommend it to any of my patients,” says Pieter Cohen, MD, a researcher at Harvard and associate professor of medicine at the Cambridge Health Alliance in Somerville, MA.

TagsBIOTINfdaLAB REPORTS
Previous Article

Cancer Vaccination Rates Rising Among U.S. Teens ...

Next Article

Can Oregon blue clay be a ideal ...

0
Shares
  • 0
  • +
  • 0
  • 0
  • 0
  • 0

admin

Related articles More from author

  • BLOGS

    Opioid Addiction Treatment Device approved by FDA

    December 2, 2017
    By admin
  • Uncategorized

    FDA approve new robotically-assisted surgical device for adult patients

    October 21, 2017
    By admin
  • BLOGS

    FDA is carefully evaluating prescription opioid medications approved to treat cough in children

    July 16, 2015
    By admin
  • FDA AlertsMedical & HealthMedical research

    FDA approves a new clinical trial for non-healing wounds.

    October 28, 2017
    By admin
  • BLOGS

    Treating Hereditary blindness by gene therapy will be a revolution in medical field

    October 20, 2017
    By admin
  • BLOGS

    US FDA approves first biosimilar for certain breast and stomach cancers treatment

    December 4, 2017
    By admin

Leave a reply Cancel reply

You may interested

  • Educational newsNotifications

    UGC-Cancelled-List of journals

  • BLOGS

    MR vaccination in india.

  • BLOGS

    Cell replacement therapy for parkinson’s disease

  • LATEST REVIEWS

  • TOP REVIEWS

  • Pharmacists are not eligible for certificate program of community health

    0
  • A New Class of Antimicrobials Has Just Been Found in Human Breast Milk Fresh super ...

    0

Timeline

  • May 17, 2025

    Resurgence of COVID-19 in Hong Kong and Singapore: A New Wave Driven by Waning Immunity and Emerging Variants

  • May 9, 2025

    How Pharmacists Support Chronic Disease Management in the Community

  • May 9, 2025

    OTC Medications: Safe Use, Common Mistakes, and Pharmacist Guidance

  • May 7, 2025

    Pharmacovigilance Explained: Why Reporting Adverse Drug Reactions Saves Lives

  • May 6, 2025

    Indian CDMOs Gain Global Momentum Amid Pharma’s Shift from China

Latest Comments

  • Pharmachronicles
    on
    February 27, 2025
    Thank you sir

    Streamlining Salaries through Payment Credit System and Other Benefits for Pharmacy Professionals: Suggestive Measures for PCI ...

  • G Krishna moorthy
    on
    February 1, 2025
    Good 👍 efforts Congratulations Continue your valuable professional services

    Streamlining Salaries through Payment Credit System and Other Benefits for Pharmacy Professionals: Suggestive Measures for PCI ...

  • Aarati sonawane
    on
    January 31, 2025
    Use in toppical application

    Role of Artificial Intelligence in 3D Printing Personalized Medication

  • Sowmya V
    on
    December 13, 2019
    Nice keep it up

    Blood Test Might Predict Pregnancy Due Date and Preterm Birth

Find us on Facebook

Follow Us on Instagram

logo

Dui viverra Faucibus aliquet quis phasellus accumsan. Donec et facilisis sociosqu sed tortor elit eu aliquid turpis ridiculus.

Fly, shall, have greater fifth spirit midst under from stars thing is, had creepeth multiply kind. Man may they’re meat years have third bring replenish air two light deep fill.

About us

  • Dr.N.Sriram, Founder CEO, Pharmachronicles, HITS college of Pharmacy, Ghatkesar, Hyderabad, India
  • 9704361947
  • pharmachronicles@gmail.com
  • Recent

  • Popular

  • Comments

  • Resurgence of COVID-19 in Hong Kong and Singapore: A New Wave Driven by Waning Immunity ...

    By Pharmachronicles
    May 17, 2025
  • How Pharmacists Support Chronic Disease Management in the Community

    By Pharmachronicles
    May 9, 2025
  • OTC Medications: Safe Use, Common Mistakes, and Pharmacist Guidance

    By Pharmachronicles
    May 9, 2025
  • Pharmacovigilance Explained: Why Reporting Adverse Drug Reactions Saves Lives

    By Pharmachronicles
    May 7, 2025
  • pharmacy credit system

    Streamlining Salaries through Payment Credit System and Other Benefits for Pharmacy Professionals: Suggestive Measures for ...

    By Pharmachronicles
    February 1, 2025
  • Blood Test Might Predict Pregnancy Due Date and Preterm Birth

    By Sundari srinidhi
    December 12, 2019
  • Ai in 3D printing

    Role of Artificial Intelligence in 3D Printing Personalized Medication

    By Pharmachronicles
    January 29, 2025
  • FDA is carefully evaluating prescription opioid medications approved to treat cough in children

    By admin
    July 16, 2015
  • Pharmachronicles
    on
    February 27, 2025

    Streamlining Salaries through Payment Credit System and Other Benefits for Pharmacy Professionals: Suggestive Measures for PCI ...

    Thank you sir
  • G Krishna moorthy
    on
    February 1, 2025

    Streamlining Salaries through Payment Credit System and Other Benefits for Pharmacy Professionals: Suggestive Measures for PCI ...

    Good 👍 efforts Congratulations ...
  • Aarati sonawane
    on
    January 31, 2025

    Role of Artificial Intelligence in 3D Printing Personalized Medication

    Use in toppical application
  • Sowmya V
    on
    December 13, 2019

    Blood Test Might Predict Pregnancy Due Date and Preterm Birth

    Nice keep it up

Photostream

    Follow us

    • Contact
    • STUDENTS ZONE
    • About Us
    © Copyright Pharmachronicles. All rights reserved.